A variety of factors are considered when determining whether or not VYXEOS (vix-e-ose) is the right treatment. These factors may include your age, your overall health, and whether you have a confirmed diagnosis of secondary acute myeloid leukemia (sAML), specifically therapy-related AML (t-AML) or AML with myelodysplasia-related changes (AML-MRC). Only a healthcare provider can decide if VYXEOS is the best course of treatment.See the treatment success story of a patient diagnosed with AML-MRC.
Benefits of VYXEOS treatment
VYXEOS provides the chance to live longer and spend less time connected to an intravenous (IV) infusion line during treatment compared to the standard chemotherapy treatment
In a clinical trial including older adult patients with t-AML or AML-MRC in which patients received either VYXEOS or the standard AML chemotherapy treatment:
Median survival time
Estimated survival at 1 year
Achieved complete remissionb
Received a hematopoietic stem cell transplant (HSCT)
- Standard chemotherapy was cytarabine 100 mg/m2 and daunorubicin 60 mg/m2.
- Complete remission is the disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured.
VYXEOS may cause serious side effects, including:
Fever, signs of infection, or bruising or bleeding which can result in serious infection and/or bleeding and possibly lead to death. You should tell your doctor about new onset fever or symptoms of infection or if you notice signs of bruising or bleeding.
Signs of heart failure such as shortness of breath or trouble breathing; swelling or fluid retention, especially in the feet, ankles, or legs; or unusual tiredness.
The most common side effects reported by patients receiving VYXEOS are bleeding events, fever, rash, swelling, nausea, sores in the mouth or throat, diarrhea, constipation, muscle pain, tiredness, stomach pain, difficulty breathing, headache, cough, decreased appetite, irregular heartbeat, pneumonia, blood infection, chills, sleep disorders, and vomiting.
These are not all of the possible side effects of VYXEOS. Be sure to speak to your healthcare team about any side effects you have.
Please see full Prescribing Information, including BOXED Warning, and discuss with your doctor.